产品货号：
Z12383
中文名称：
Caspase 10/CASP10抗体
英文名称：
Anti-Caspase 10/CASP10 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Caspase 10/CASP10 Antibody |
| 指标别名 | ALPS2;Apoptotic protease Mch 4;CASP 10;CASP10;Caspase 10;Caspase 10/p23/17/p12;Caspase10;FLICE2;ICE like apoptotic protease 4;MCH4 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IF,ICC |
| 基因名称 | CASP10 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Caspase-10 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Caspase-10.The immunogen is located within amino acids 240 - 290 of Caspase-10. |
| 计算分子量 | 59kDa |
| 成分 | Caspase-10 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Caspase-10 Antibody is Antibody is DEAE purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family.A novel ICE/CED-3 protease was identified recently,designated FLICE2 and Mch4 and renamed as caspase-10.Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors.Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis.Caspase-10 cleaves and activates caspase-3,-4,-6,-7,-8 and -9,which causes the proteolytic cleavage of many key proteins such as PARP.Cleavage of PARP occurs in many different systems during apoptosis and is the hallmark of programmed cell death.Caspase-10 is expressed in many tissues and cell lines. |
| Uniprot ID | Q92851 |
| 基因名全称 | Caspase 10,apoptosis-related cysteine peptidase |
| 蛋白名全称 | Caspase 10,apoptosis-related cysteine peptidase |
| 推荐稀释比 | Caspase-10 antibody can be used for detection of caspase-10 by Western blot 1μg/mL.A 59kDa band can be detected.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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